Activation of a Toxic Component of Clostridium botulinum Types C and D by Trypsin.
نویسندگان
چکیده
[This corrects the article on p. 108 in vol. 24.].
منابع مشابه
Purification and activation of Clostridium botulinum type E toxin.
Type E strains of Clostridium botulinum tend to produce toxin of relatively low mouse killing power (administered intraperitoneally) in relation to its high lethality per os for man. The explanation of this peculiarity seems to lie in the phenomenon of "activation," whereby type E toxin, when exposed at an appropriate pH in vitro to certain bacterial enzymes (Dolman, 1953, 1957a; Sakaguchi and ...
متن کاملActivation phenomenon of Clostridium botulinum type E toxin.
Gerwing, Julia (The University of British Columbia, Vancouver, Canada), Claude E. Dolman, and David A. Arnott. Activation phenomenon of Clostridium botulinum type E toxin. J. Bacteriol. 84:302-306. 1962-Highly purified preparations of both nonactivated and trypsin-activated type E botulinus toxins have been analyzed in an ultracentrifuge. Untreated botulinus type E toxin was found to have a sed...
متن کاملActivation of Clostridium botulinum type B toxin by an endogenous enzyme.
It was previously postulated, based on indirect evidence, that Clostridium botulinum type B produces neurotoxin which is initially of low toxicity but which then becomes activated to highly toxic form by the action of an endogenous enzyme(s). The first direct in vitro experimental evidence in support of this hypothesis is presented here. The mildly active toxin (progenitor toxin) produced by C....
متن کاملThe toxic antigenic factors produced by Clostridium botulinum types C and D.
JANSEN, B. C. The toxic antigenic factors produced by Clostridium botulinum types C and D. Onderstepoort ]. vet Res., 38 (2), 93-98 (1971). The toxic factors produced by Clostridium botulinum (Van Ermengem, 1896), types C and D were determined. Monospecific antisera were prepared against the different factors. It was shown that type Coc produces factors C" C2 and D; type C f3 produces factor C ...
متن کاملCharacterization of Clostridium botulinum spores and its toxin in honey
Botulism is a serious paralytic disease caused by Clostridium botulinum toxin in foods. There are seven recognized serotypes of botulinum neurotoxins among which the principal prevalent types in humans include A, B and E. Infant botulism results from intestinal colonization and toxin production by C. botulinum spores in babies less than 1 year old. Honey is the most important food discriminated...
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عنوان ژورنال:
- Applied microbiology
دوره 24 1 شماره
صفحات -
تاریخ انتشار 1972